KNEE3D

Here we feature research publications from our team before joining KNEE3D that show how we have developed CT analysis of the knee with a wide-ranging capability of our techniques.

Joint space mapping

Turmezei TD, B Low S, Rupret S, Treece GM, Gee AH, MacKay JW, Lynch JA, Poole KES, Segal NA. Quantitative Three-dimensional Assessment of Knee Joint Space Width from Weight-bearing CT. Radiology. 2021 Jun;299(3):649-659.

doi: 10.1148/radiol.2021203928

WBCT versus x-ray

Segal NA ... Anderson DD. Improved responsiveness to change in joint space width over 24-month follow-up: comparison of 3D JSW on weight-bearing CT vs 2D JSW on radiographs in the MOST study. Osteoarthritis Cartilage. 2023 Mar;31(3):406-413.

doi: 10.1016/j.joca.2022.12.002

Bone treatment effects

Poole KE, Treece GM, Pearson RA, Gee AH ... Whitmarsh T. Romosozumab Enhances Vertebral Bone Structure in Women With Low Bone Density. J Bone Miner Res. 2022 Feb;37(2):256-264.

doi: 10.1002/jbmr.4465

Multiparametric bone

Turmezei TD ... Treece GM, Gee AH, MacKay JW, Lynch JA, Poole KE, Segal NA. Multiparametric 3-D analysis of bone and joint space width at the knee from weight bearing computed tomography. Osteoarthr Imaging. 2022 Jun;2(2):100069.

doi: 10.1016/j.ostima.2022.100069

WBCT protocol needs

Brinch S ... Turmezei T, Streekstra GJ, Hansen P. Weight-bearing cone-beam CT: the need for standardised acquisition protocols and measurements to fulfill high expectations-a review of the literature. Skeletal Radiol. 2023 Jun;52(6):1073-1088.

doi: 10.1007/s00256-022-04223-1

Subchondral bone CT

Schadow JE ... Segal NA ... Turmezei T, Stok KS. Systematic review of computed tomography parameters used for the assessment of subchondral bone in osteoarthritis. Bone. 2024 Jan;178:116948.

doi: 10.1016/j.bone.2023.116948

Early osteoarthritis

Li X, Roemer FW, Cicuttini F, MacKay JW, Turmezei T, Link TM. Early knee OA definition-what do we know at this stage? An imaging perspective. Ther Adv Musculoskelet Dis. 2023 Mar 14;15:1759720X231158204.

doi: 10.1177/1759720X231158204

CT and metal artefact

Whitmarsh T, Treece GM, Gee AH, Poole KES. An exploratory study into measuring the cortical bone thickness from CT in the presence of metal implants. Int J Comput Assist Radiol Surg. 2017 Dec;12(12):2079-2086.

doi: 10.1007/s11548-017-1539-z

Latest OA imaging

Hayashi D, Roemer FW, Link T, Li X, Kogan F, Segal NA, Omoumi P, Guermazi A. Latest advancements in imaging techniques in OA. Ther Adv Musculoskelet Dis. 2022 Dec 26;14:1759720X221146621.

doi: 10.1177/1759720X221146621