KNEE3D
CT Osteoarthritis Knee Score (COAKS)
REPLACE X-RAY GRADING WITH 3D CT FEATURE SCORING
Computed tomography (CT) gives far superior 3D visualisation of x-ray features of osteoarthritis (OA) than radiographs, yet the distribution of these features is still not easy to grasp from an entire imging data set.
We can provide expert semi-quantitative COAKS grading of the cardial OA features of joint space narrowing (J), osteophytes (O), subchondral cysts (C), and subchondral sclerosis (S) on a scale of 0-3 at all 4 compartments at the knee: medial tibiofemoral (MTF), lateral tibiofemoral (LTF), patellofemoral (PF), and proximal tibiofibular (PTF).
Joint space narrowing is assessed from weight baring CT only, but all other features can be assessed with standard non-weight bearing CT.
DON'T MISS EARLY FEATURES OF OSTEOARTHRITIS
Despite a first glance that might suggest no evidence of structural OA in this individual, COAKS reveals a different picture suggest subtle early osteoarthritis in the form of tiny marginal osteophytes, <50% MTF joint space narrowing and suspected PF sclerosis - a non-expert may miss these subtle signs.
The COAK structural patterning heatmap summarises these features in an easy to view, east to interpret 4 x 4 matrix that can deliver feature "sum" scores, individual compartment and overall joint "multicomponent" scores.
OPTIMISED OSTEOARTHRITIS STRATIFICATION
Here we see the example of an individual with widespread features of OA, most notably with complete MTF joint space narrowing and prominent subchondral cysts/sclerosis with moderate (grade 2) osteophytosis at worst.
If you wanted only medial tibiofemoral morphotypes in your study and did not want to be confounded by disease in other compartments, then COAKS is an indispensible service we can provide.
Click here for the original COAKS paper that involved our team before starting with KNEE3D.
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